Thalidomide-5-Br
Based on 1 Customer Validation
Thalidomide-5-Br is an analog of Thalidomide (HY-14658). Thalidomide-5-Br serves as an intermediate for research related to the generation of Thalidomide derivatives.
For research use only. We do not sell to patients.
- Purity: 98.92%
- CAS No.: 26166-92-7
- Formula: C13H9BrN2O4
- Molecular Weight:337.13
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
Biological Activity
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Cereblon |
Thalidomide-5-Br (compound 4) serves as the core halogenated precursor for the synthesis of C4-position N-aryl Thalidomide (HY-14658) derivatives, and is compatible with various palladium-catalyzed systems for Buchwald-Hartwig C-N coupling screening[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 26166-92-7
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Appearance Solid
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Molecular Weight 337.13
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Formula C13H9BrN2O4
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Color Off-white to gray
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SMILES
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(Br)=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
DMSO : 3.33 mg/mL (9.88 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9662 mL | 14.8311 mL | 29.6621 mL | 74.1554 mL |
| 5 mM | 0.5932 mL | 2.9662 mL | 5.9324 mL | 14.8311 mL |