AX-53802
AX-53802 is a ferroptosis inducer targeting GPX4 with an IC50 of 0.34 µM. AX-53802 forms a covalent bond with GPX4, initiating membrane translocation directly upon binding. AX-53802 and FAK/Src inhibitors promotes cell death. AX-53802 can be used for cancer study.
For research use only. We do not sell to patients.
- CAS No.: 1008482-71-0
- Formula: C23H21FN2O4
- Molecular Weight:408.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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GPX4 |
Chemical Information
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CAS No. 1008482-71-0
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Molecular Weight 408.42
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Formula C23H21FN2O4
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SMILES
O=C(NC1CCCC1)C(C2=C(F)C=CC=C2)N(C(C#C)=O)C3=CC=C4C(OCO4)=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)