1008482-71-0
1008482-71-0
Chemical Structure
AX-53802
- CAS No.: 1008482-71-0
- Formula:C23H21FN2O4
- Molecular Weight:408.42
InChIKey: MULUHYCTKIAUDD-UHFFFAOYSA-N
SMILES: O=C(NC1CCCC1)C(C2=C(F)C=CC=C2)N(C(C#C)=O)C3=CC=C4C(OCO4)=C3
Biological Activity: AX-53802 is a ferroptosis inducer targeting GPX4 with an IC50 of 0.34 µM. AX-53802 forms a covalent bond with GPX4, initiating membrane translocation directly upon binding. AX-53802 and FAK/Src inhibitors promotes cell death. AX-53802 can be used for cancer study[1].
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AX-53802 | AX-53802 is a ferroptosis inducer targeting GPX4 with an IC50 of 0.34 µM. AX-53802 forms a covalent bond with GPX4, initiating membrane translocation directly upon binding. AX-53802 and FAK/Src inhibitors promotes cell death. AX-53802 can be used for cancer study. | |||||||||||||||||||||
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References
Keywords
