Azintuxizumab vedotin
Based on 1 Customer Validation
Azintuxizumab vedotin (ABBV-838) is an antibody–drug conjugate (ADC) targeting a unique epitope of CD2 subset 1, a cell-surface glycoprotein expressed on multiple myeloma cells.
For research use only. We do not sell to patients.
- Purity: 98.00%
- CAS No.: 1826819-58-2
- Molecular Weight:146.036 kDa
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Storage:
-80°C, protect from light
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
SLAMF7/CS1
Azintuxizumab vedotin (ABBV-838) is an ADC comprising a humanized recombinant immunoglobulin G1κ directed against a unique epitope of CD2 subset 1 (CS1, also known as SLAMF7) conjugated to the cytotoxic monomethyl auristatin E (MMAE) through a valine-citrulline linker[1].
Azintuxizumab vedotin shows potent cytotoxic activity against cancer cells that expressed CS1[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
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Human IgG1 kappa
Chemical Information
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CAS No. 1826819-58-2
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Appearance Liquid
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Molecular Weight 146.036 kDa
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Color Colorless to light yellow
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SMILES
[Azintuxizumab vedotin]
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Synonyms
ABBV-838
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Shipping
Shipping with dry ice.
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Storage
-80°C, protect from light
Purity & Documentation
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Data Sheet (265 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Azintuxizumab vedotin Related Classifications
HY-P99454 Related Classifications
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