1. Anti-infection
  2. Bacterial
    Antibiotic
  3. Balofloxacin dihydrate

Balofloxacin dihydrate (Synonyms: Q-35 dihydrate)

Cat. No.: HY-B0159A
Handling Instructions

Balofloxacin dihydrate (Q-35 dihydrate) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin dihydrate can be used for the research of respiratory, intestinal, and urinary tract infections.

For research use only. We do not sell to patients.

Balofloxacin dihydrate Chemical Structure

Balofloxacin dihydrate Chemical Structure

CAS No. : 151060-21-8

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Description

Balofloxacin dihydrate (Q-35 dihydrate) is an orally active fluoroquinolone antibiotic with broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin dihydrate can be used for the research of respiratory, intestinal, and urinary tract infections[1][2].

In Vitro

Balofloxacin (25 mg/mL; 1 h) decreases the growth of S. aureus that adhered to human corneal epithelial cells (HCECs)[2].
Balofloxacin inhibits the S. aureus ATCC 25923, with a MIC of 0.125 mg/mL[2].
Balofloxacin (0.05-500 μg/mL; 72 h) does not induce toxicity on the HCECs at a low concentration, such as 0.625 mg/mL[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Balofloxacin (200 mg/kg/day; p.o. for 5 d) reduces the counts of viable M. pneumonia in the lungs of hamsters[3].
Balofloxacin eye drops (0.5%) is effective in S. aureus bacterial keratitis of rabbits[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

425.45

Formula

C₂₀H₂₈FN₃O₆

CAS No.
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Balofloxacin dihydrate
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HY-B0159A
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