2-oxoadipate dehydrogenase complex component E1
Definition:
References:
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[1]. Natalia S Nemeria, et al. Evidence for functional and regulatory cross-talk between the tricarboxylic acid cycle 2-oxoglutarate dehydrogenase complex and 2-oxoadipate dehydrogenase on the l-lysine, l-hydroxylysine and l-tryptophan degradation pathways from studies in vitro. Biochim Biophys Acta Bioenerg. 2018 Sep;1859(9):932-939. [Content Brief]
[2]. João Leandro, et al. Inhibition and Crystal Structure of the Human DHTKD1-Thiamin Diphosphate Complex. ACS Chem Biol. 2020 Aug 21;15(8):2041-2047. [Content Brief]
[3]. Gustavo A Bezerra, et al. Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism. IUCrJ. 2020 Jun 10;7(Pt 4):693-706. [Content Brief]
[4]. Xu Zhang, et al. Structure-function analyses of the G729R 2-oxoadipate dehydrogenase genetic variant associated with a disorder of l-lysine metabolism. J Biol Chem. 2020 Jun 5;295(23):8078-8095. [Content Brief]
[5]. Natalia S Nemeria, et al. The mitochondrial 2-oxoadipate and 2-oxoglutarate dehydrogenase complexes share their E2 and E3 components for their function and both generate reactive oxygen species. Free Radic Biol Med. 2018 Feb 1;115:136-145. [Content Brief]
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