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A549/CDDP

Definition:

A549/CDDP is a human cancer cell line derived from Lung and associated with Lung adenocarcinoma. A549/CDDP is a resistant derivative of A-549 selected against Cisplatin (CDDP. A549/CDDP is used as an in vitro model of Lung adenocarcinoma to investigate Wnt signaling, hypoxic responses, and drug resistance.

References:

[1]. Jiang P, et al. NEAT1 contributes to the CSC-like traits of A549/CDDP cells via activating Wnt signaling pathway. Chemico-biological interactions. 2018;296:154-161.

[2]. Min L, et al. Hypoxia-induced increases in A549/CDDP cell drug resistance are reversed by RNA interference of HIF-1α expression. Molecular medicine reports. 2012;5(1):228-32.

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