C12 NBD Globotriaosylceramide
C12 NBD galactosylceramide is a biologically active derivative of galactosylceramide that is tagged with a fluorescent C12 nitrobenzoxadiazole (C12 NBD) group. C12 NBD galactosylceramide has been used to detect ceramide trihexoside.
For research use only. We do not sell to patients.
- CAS No.: 2692623-26-8
- Formula: C54H91N5O21
- Molecular Weight:1146.32
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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HY-W356117
C6 NBD GlucosylceramideGlucosylceramide Fluorescent Derivative -
HY-D1577
C6 NBD LactosylceramideFluorescent Dye -
HY-141575
C12-NBD-ceramideFluorescent Dye -
HY-141576
C6-NBD SphinganineFatty Acid Fluorescent Marker -
HY-141577
C12-NBD SphinganineCeramidase Substrate -
HY-D1575
C6 NBD GalactosylceramideGCase Substrate -
HY-147178
C-6 NBD-dihydro-CeramideCeramides -
HY-D1580
C12 NBD LactosylceramideFluorescent Dye -
HY-D1521
N-(NBD-Aminolauroyl)safingolFluorescent Dye -
HY-145493
C12 NBD GalactosylceramideFluorescent Dye
Biological Activity
Description
In Vitro
C12 NBD globotriaosylceramide accumulates in human umbilical vascular endothelial cells (HUVECs) treated with the α-galactosidase A inhibitor in a concentration-dependent manner[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Emission (Em)
525
Chemical Information
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CAS No. 2692623-26-8
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Molecular Weight 1146.32
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Formula C54H91N5O21
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SMILES
O=C(CCCCCCCCCCCNC1=CC=C(C2=NON=C12)[N+]([O-])=O)N[C@@H](CO[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O[C@@]4(O[C@@H]([C@@H]([C@@H]([C@H]4O)O)O[C@@]5([C@@H]([C@H]([C@H]([C@H](O5)CO)O)O)O)[H])CO)[H])O)O)[C@@H](/C=C/CCCCCCCCCCCCC)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Kassiani Kytidou, et al. Nicotiana benthamiana α-galactosidase A1.1 can functionally complement human α-galactosidase A deficiency associated with Fabry disease. J Biol Chem. 2018 Jun 29;293(26):10042-10058. [Content Brief]
[2]. Janet Hsu, et al. Enhanced endothelial delivery and biochemical effects of α-galactosidase by ICAM-1-targeted nanocarriers for Fabry disease. J Control Release. 2011 Feb 10;149(3):323-31. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
C12 NBD Globotriaosylceramide Related Classifications
HY-D1579 Related Classifications
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