17-Hydroxyjolkinolide A
17-Hydroxyjolkinolide A (Caudicifolin; Fischeriana A) is an insect feeding inhibitor isolated from the roots of spurge. 17-Hydroxyjolkinolide A induces grain aversion in S. zeamais and T. castaneum adults, with EC50s of 631.9 ppm and 656.5 ppm, respectively.
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- CAS No.: 65388-16-1
- Formule: C20H26O4
- Masse moléculaire:330.42
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BV-2 | IC50 |
9.1 μM
Compound: 14
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Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by Griess assay
Antiinflammatory activity in mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production incubated for 24 hrs by Griess assay
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[PMID: 31180680] |
| HCT-15 | IC50 |
13 μM
Compound: 6e
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Cytotoxicity against human HCT-15 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human HCT-15 cells incubated for 48 hrs by MTT assay
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[PMID: 33289552] |
| LNCaP C4-2B | IC50 |
2.2 μM
Compound: 6e
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Cytotoxicity against human LNCaP C4-2B cells incubated for 48 hrs by MTT assay
Cytotoxicity against human LNCaP C4-2B cells incubated for 48 hrs by MTT assay
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[PMID: 33289552] |
| MDA-MB-231 | IC50 |
8.8 μM
Compound: 6e
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Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay
Cytotoxicity against human MDA-MB-231 cells incubated for 48 hrs by MTT assay
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[PMID: 33289552] |
Chemical Information
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CAS No. 65388-16-1
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Masse moléculaire 330.42
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Formule C20H26O4
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SMILES
C[C@]12[C@@]3([H])[C@@]4(CC[C@]1([H])C(C)(CCC2)C)[C@](C(C(O5)=C3)=C(CO)C5=O)([H])O4
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Synonyms
Caudicifolin; Fischeriana A
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
17-Hydroxyjolkinolide A Related Classifications
HY-N12428 Related Classifications
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