Altemicidin
Altemicidin is a monoterpene alkaloid originally isolated from S. sioyaensis with acaricidal and anticancer activities. It is acaricidal to two-spotted spider mites (T. urticae) in a greenhouse pot test at concentrations of 10 and 100 ppm. Altemicidin inhibits the growth of murine L1210 lymphocytic leukemia and IMC carcinoma cells (IC50s=0.84 and 0.82 μg/mL, respectively). It is toxic to mice with an LD50 value of 0.3 mg/kg.
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- CAS No.: 125399-82-8
- Formule: C13H20N4O7S
- Masse moléculaire:376.39
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| L1210 | IC50 |
0.84 μM
Compound: 9
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Antiproliferative activity against mouse L1210 cells assessed as inhibition of cell proliferation incubated for 48 hrs by Coulter counter method
Antiproliferative activity against mouse L1210 cells assessed as inhibition of cell proliferation incubated for 48 hrs by Coulter counter method
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[PMID: 33160760] |
| L1210 | IC50 |
2.12 μM
Compound: 1
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Cytotoxicity against mouse L1210 cells assessed as growth inhibition after 48 hrs by coulter counter analysis
Cytotoxicity against mouse L1210 cells assessed as growth inhibition after 48 hrs by coulter counter analysis
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[PMID: 26035239] |
Chemical Information
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CAS No. 125399-82-8
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Masse moléculaire 376.39
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Formule C13H20N4O7S
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SMILES
O=C(C[S](N)(=O)=O)N[C@@]1([C@@](CN2C)([H])[C@@](C(C(N)=O)=C2)([H])C[C@@H]1O)C(O)=O
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Synonyms
(-)-Altemicidin
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Altemicidin Related Classifications
HY-N10653 Related Classifications
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