Antibacterial agent 333

Antibacterial agent 333 (Compound 7h) potently inhibits the growth of Vibrio parahaemolyticus ATCC 17802 with an MIC of 8 μg/mL and inhibits Vibrio alginolyticus CICC 21664 with an MIC of 16 μg/mL^[1].
Antibacterial agent 333 (4-32 μg/mL) inhibits Vibrio parahaemolyticus biofilm formation^[1].
Antibacterial agent 333 (8-32 μg/mL; 0-12 h) exhibits rapid, concentration-dependent bactericidal activity against Vibrio parahaemolyticus, reducing bacterial counts below the detection limit within 6 h at 16 μg/mL (2×MIC) and within 4 h at 32 μg/mL (4×MIC)^[1].
Antibacterial agent 333 (16 μg/mL) disrupts the inner membrane permeability of Vibrio parahaemolyticus^[1].
Antibacterial agent 333 (4-32 μg/mL; 24-72 h) shows no cytotoxicity toward RAW 264.7 and HEK 293 T cells, with cell viability remaining above 80% even at the highest tested concentration^[1].
Antibacterial agent 333 (4-32 μg/mL) exhibits no hemolytic activity against sheep red blood cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.