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Cat. No.: HY-146686

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BuChE-IN-3

BuChE-IN-3 (Compound C4) is a potent inhibitor of BuChE with an IC₅₀ of 8.3 nM. BuChE-IN-3 exhibits mild antioxidant capacity, nontoxicity, lipophilicity and neuroprotective activity.

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CAS No.: 2499488-78-5
Formule: C₂₁H₂₁F₂N₃O₄S
Masse moléculaire:449.47

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

BuChE-IN-3 Chemical Structure

CAS No.: 2499488-78-5

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

BuChE-IN-3 (Compound C4) is a potent inhibitor of BuChE with an IC₅₀ of 8.3 nM. BuChE-IN-3 exhibits mild antioxidant capacity, nontoxicity, lipophilicity and neuroprotective activity^[1].

Voir tous les produits spécifiques à Isoform Cholinesterase (ChE) :

AChE
BChE

Chemical Information

CAS No. 2499488-78-5
Masse moléculaire 449.47
Formule C₂₁H₂₁F₂N₃O₄S
SMILES

O=S1(CCC2=C(N(N=C2CN(CC3=CC=C(C=C3)F)CCO)C4=CC=CC=C4F)O1)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Zhang Z, et al. The structure-based optimization of δ-sultone-fused pyrazoles as selective BuChE inhibitors. Eur J Med Chem. 2020 Sep 1;201:112273. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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BuChE-IN-3

Voir tous les produits spécifiques à Isoform Cholinesterase (ChE)

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

BuChE-IN-3 Related Classifications

HY-146686 Related Classifications