Carbiphene
Carbiphene is a GABAA receptor allosteric modulator. Carbiphene inhibits [35S] TBPS binding and enhances [3H] muscimol binding on rat forebrain membranes, acting on specific GABAA receptor subsets. Carbiphene can be used in research related to schizophrenia.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 15687-16-8
- Formule: C28H34N2O2
- Masse moléculaire:430.59
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
Carbiphene inhibits the binding of [35S]TBPS to rat whole forebrain membranes with an IC50 of 12 μM[1].
Carbiphene enhances the binding of [3H]MUS to rat whole forebrain membranes, with an EC50 of 34 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 15687-16-8
-
Masse moléculaire 430.59
-
Formule C28H34N2O2
-
SMILES
O=C(N(C)CCN(C)CCC=1C=CC=CC1)C(OCC)(C=2C=CC=CC2)C=3C=CC=CC3
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Squires RF, et al. Additivities of compounds that increase the numbers of high affinity [3H]muscimol binding sites by different amounts define more than 9 GABA(A) receptor complexes in rat forebrain: implications for schizophrenia and clozapine research. Neurochem Res. 2000;25(12):1587-1601. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Carbiphene Related Classifications
HY-105567 Related Classifications
Powered by Bioz