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Cat. No.: HY-111121

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cBu-Cit-OH

(Synonyms: Mal-cyclobutane-1,1-dicarboxamide-Cit-PAB)

cBu-Cit-OH (Mal-cyclobutane-1) is an ADC Linker that can be used to synthesize ADCs.

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CAS No.: 1799663-03-8
Formule: C₂₈H₃₈N₆O₇
Masse moléculaire:570.64

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

cBu-Cit-OH Chemical Structure

CAS No.: 1799663-03-8

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Description

cBu-Cit-OH (Mal-cyclobutane-1) is an ADC Linker that can be used to synthesize ADCs^[1].

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Chemical Information

CAS No. 1799663-03-8
Masse moléculaire 570.64
Formule C₂₈H₃₈N₆O₇
SMILES

OCC1=CC=C(NC([C@H](CCCNC(N)=O)NC(C2(C(NCCCCCN3C(C=CC3=O)=O)=O)CCC2)=O)=O)C=C1
Synonyms

Mal-cyclobutane-1,1-dicarboxamide-Cit-PAB
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Wei B, et al. Discovery of Peptidomimetic Antibody-Drug Conjugate Linkers with Enhanced Protease Specificity. J Med Chem. 2018 Feb 8;61(3):989-1000. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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cBu-Cit-OH

Voir tous les produits spécifiques à Isoform ADC Linkers

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

cBu-Cit-OH Related Classifications

HY-111121 Related Classifications