CSF1R-IN-8
CSF1R-IN-8 (Compound 22) is a CSF-1R inhibitor with an IC50 of 0.012 μM.
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- CAS No.: 2765301-60-6
- Formule: C24H22N4O4
- Masse moléculaire:430.46
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Description
IC50 & Target
CSF-1R[1]
In Vitro
CSF1R-IN-8 (Compound 22) inhibits CSF-1R phosphorylation activity with an IC50 of 0.009 μM in THP-1 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 2765301-60-6
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Masse moléculaire 430.46
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Formule C24H22N4O4
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SMILES
COC1=C(N=CC(OC2=CN3C(C(N)=CN=C3C=C2)=O)=C1)OCC4=CC=C(C=C4)C5CC5
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocole
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)