DAT-230
DAT-230 is a microtubule inhibitor. DAT-230 induces cell apoptosis and results in microtubule de-polymerization and G2/M phase arrest. DAT-230 inhibits cell growth in vitro and in vivo.
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- CAS No.: 1504583-00-9
- Formule: C20H21NO2S
- Masse moléculaire:339.45
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
Chemical Information
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CAS No. 1504583-00-9
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Masse moléculaire 339.45
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Formule C20H21NO2S
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SMILES
NC1=CC(C2=C(C3=CC(C)=C(C)C(OC)=C3)SC=C2)=CC=C1OC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Qiao F, et al. DAT-230, a Novel Microtubule Inhibitor, Induced Aberrant Mitosis and Apoptosis in SGC-7901 Cells. Biol Pharm Bull. 2013;36(2):193-201. [Content Brief]
[2]. Tang J, et al. Application of an ultra-performance liquid chromatography method with tandem mass spectrometry to pharmacokinetics, tissue distribution and excretion in the study of DAT-230, a novel tubulin-binding agent candidate, in rats. J Pharm Biomed Anal. 2015;110:49-57. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)