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Cat. No.: HY-100623

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Dofetilide N-oxide

(Synonyms: UK-116856)

Dofetilide N-oxide (UK-116856) is a metabolite of Dofetilide. Dofetilide is a class III antiarrhythmic agent that blocks potassium channels.

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CAS No.: 144449-71-8
Formule: C₁₉H₂₇N₃O₆S₂
Masse moléculaire:457.56

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Dofetilide N-oxide Chemical Structure

CAS No.: 144449-71-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

Dofetilide N-oxide (UK-116856) is a metabolite of Dofetilide. Dofetilide is a class III antiarrhythmic agent that blocks potassium channels^[1]^[2].

IC₅₀ & Target

Potassium channels^[1]^[2]

Chemical Information

CAS No. 144449-71-8
Masse moléculaire 457.56
Formule C₁₉H₂₇N₃O₆S₂
SMILES

CS(=O)(NC1=CC=C(CC[N+](CCOC2=CC=C(NS(=O)(C)=O)C=C2)(C)[O-])C=C1)=O
Synonyms

UK-116856
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Maisch B, et al. Pregnancy and cardiomyopathies. Herz. 2003 May;28(3):196-208. [Content Brief]

[2]. Snyders, D.J. and A. Chaudhary, High affinity open channel block by dofetilide of HERG expressed in a human cell line. Mol Pharmacol, 1996. 49(6): p. 949-55. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration Concentration

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Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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(17R,18S)-Epoxyeicosatetraenoic acid

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Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Dofetilide N-oxide

Quinaprilat

Mabuterol

3-O-Methyl-DL-DOPA

Acebutolol

3-O-Methyl-DL-DOPA (Standard)

7-Hydroxywarfarin

Hydroxymetronidazole

Mabuterol (Standard)

Quinaprilat (Standard)

Wy-45494 hydrochloride (Standard)

(17R,18S)-Epoxyeicosatetraenoic acid

Wy-45494 hydrochloride

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Dofetilide N-oxide Related Classifications

HY-100623 Related Classifications