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Lenzilumab

(Synonyms: KB 003)
2 Cited Publications
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Based on 2 publication(s) in Google Scholar

Lenzilumab (KB 003) is a human monoclonal antibody targeting CSF2/GM-CSF for COVID-19, chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML) studies.

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  • Pureté: 99.64%
  • CAS No.: 1229575-09-0
  • Masse moléculaire:145.72 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Lenzilumab
  • Experimental Validation Results for Lenzilumab
  • Experimental Validation Results for Lenzilumab
  • Experimental Validation Results for Lenzilumab
  • Lenzilumab Chemical Structure
    Lenzilumab Chemical Structure
CAS No.: 1229575-09-0
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Lenzilumab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Loaded Lenzilumab on AHC2 biosensor, can bind GM-CSF Protein, Human (His, HY-P7016C) with an affinity constant of 5.364E-10 M as determined in BLI assay.

  • 1/16

    Lenzilumab(HY-P99207) neutralizes Recombinant Human GM-CSF (HY-P7016A) induced proliferation in the TF-1 human erythroleukemic cell line. The Neutralization Dose (ND50) for this effect is 0.02545μg/mL in the presence of 0.5 ng/mL Recombinant Human GM-CSF.

  • 1/16

    Lenzilumab purchased from MedChemExpress. Usage Cited in: Arthritis Res Ther. 2025 Sep 26;27(1):180. [Abstract]

    Customer Validation
     Extracellular acidification rate (ECAR) measured by Seahorse assay in HMDMs exposed to RA serum with or without IL-1RN, infliximab, or lenzilumab (10 µg/mL).

  • Lenzilumab Chemical Structure
    1/16
  • Lenzilumab
  • Loaded Lenzilumab on AHC2 biosensor, can bind GM-CSF Protein, Human (His, HY-P7016C) with an affinity constant of 5.364E-10 M as determined in BLI assay.
  • Lenzilumab(HY-P99207) neutralizes Recombinant Human GM-CSF (HY-P7016A) induced proliferation in the TF-1 human erythroleukemic cell line. The Neutralization Dose (ND50) for this effect is 0.02545μg/mL in the presence of 0.5 ng/mL Recombinant Human GM-CSF.