NSD-IN-5
NSD-IN-5 is a nuclear receptor-binding SET domain (NSD) inhibitor with IC50 values of 6 nM and < 1 nM against NSD1 and NSD2, respectively. NSD-IN-5 can be used in research related to multiple myeloma.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 3034213-62-9
- Formule: C26H28F2N8O2
- Masse moléculaire:522.55
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Voir tous les produits spécifiques à Isoform Histone Methyltransferase
More
Activité biologique
|
NSD2 < 1 nM (IC50) |
NSD1 6 nM (IC50) |
NSD-IN-5 potently inhibits NSD1 histone lysine methyltransferase activity in a cell-free assay with an average IC50 of 6 nM[1].
NSD-IN-5 potently inhibits NSD2 histone lysine methyltransferase activity in a cell-free assay with an average IC50 of <1 nM[1].
NSD-IN-5 inhibits H3K36 dimethylation in KMS11 cells with an average IC50 of 6 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 3034213-62-9
-
Masse moléculaire 522.55
-
Formule C26H28F2N8O2
-
SMILES
FC(C=C(C(F)=C1)OC)=C1C2=NC=C(N3C[C@](N)(CCC3)C(NC)=O)C(CC4=CN=C5N4C=CN=C5N)=C2
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
NSD-IN-5 Related Classifications
HY-177400 Related Classifications
Powered by Bioz