Plipastatin A1
Plipastatin A1 (Fengycin IX; SNA-60-367-3) is a lipopeptide with phospholipase A2 inhibitory activity. Plipastatin A1 inhibits conidial germination of Botrytis cinerea in vitro and reduces the incidence of gray mold on tomato leaves. Plipastatin A1 is applicable to research related to gray mold[1][2].
For research use only. We do not sell to patients.
- CAS No.: 103651-09-8
- Formula: C72H110N12O20
- Molecular Weight:1463.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Phospholipase Isoforms
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Biological Activity
Plipastatin A1 (1-50 μM; 12-24 h) significantly inhibits the in vitro germination of conidia of Botrytis cinerea[2].
Plipastatin A1 (50 μM) significantly reduces the spread of gray mold disease lesions on tomato leaf discs inoculated with Botrytis cinerea[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 103651-09-8
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Molecular Weight 1463.71
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Formula C72H110N12O20
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Synonyms
Fengycin IX; SNA-60-367-3
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Sequence
{(3R)-3-hydroxy-1-oxohexadecyl}-Glu-{d-Orn}-Tyr-{d-Thr}-Glu-{d-Ala}-Pro-Gln-{d-Tyr}-Ile (Lactam bridge: Tyr3-Ile10)
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Sequence Shortening
{(3R)-3-hydroxy-1-oxohexadecyl}-E-{d-Orn}-Y{d-Thr}-E-{d-Ala}-PQ{d-Tyr}-I (Lactam bridge: Tyr3-Ile10)
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Honma M, et al. Termination of the structural confusion between plipastatin A1 and fengycin IX. Bioorg Med Chem. 2012;20(12):3793-3798. [Content Brief]
[2]. Ma Z, et al. Plipastatin A1 produced by a marine sediment-derived Bacillus amyloliquefaciens SH-B74 contributes to the control of gray mold disease in tomato. 3 Biotech. 2018 Feb;8(2):125. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Plipastatin A1 Related Classifications
Cat. No.: HY-P10447
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- Plipastatin A1
- 103651-09-8
- Fengycin IX
- SNA-60-367-3
- Plipastatin A 1
- Plipastatin A-1
- Phospholipase
- Fungal
- Bacillus cereus BMG3O2-fF67
- tomato leaf discs
- potassium salt
- Bacillus subtilis H336B
- tomato leaves
- Bacillus amyloliquefaciens SH-B74
- phospholipase A2 inhibitor
- gray mold disease
- conidia germination
- Botrytis cinerea
- Inhibitor
- inhibitor
- inhibit