Pomalidomide-propargyl
Based on 1 Customer Validation
Pomalidomide-propargyl contains an E3 ligand and a terminal alkyl group ready for click conjugation. Pomalidomide-propargyl is ready for conjugation to target proteins for PROTAC.
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- Pureté: 98.10%
- CAS No.: 2154342-25-1
- Formule: C16H13N3O4
- Masse moléculaire:311.30
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Stockage:
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
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Help & FAQs
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Activité biologique
Description
IC50 & Target
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Cereblon |
Chemical Information
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CAS No. 2154342-25-1
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Appearance Solid
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Masse moléculaire 311.30
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Formule C16H13N3O4
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Color Light yellow to yellow
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SMILES
O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCC#C)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (321.23 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (246 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2123 mL | 16.0617 mL | 32.1234 mL | 80.3084 mL |
| 5 mM | 0.6425 mL | 3.2123 mL | 6.4247 mL | 16.0617 mL | |
| 10 mM | 0.3212 mL | 1.6062 mL | 3.2123 mL | 8.0308 mL | |
| 15 mM | 0.2142 mL | 1.0708 mL | 2.1416 mL | 5.3539 mL | |
| 20 mM | 0.1606 mL | 0.8031 mL | 1.6062 mL | 4.0154 mL | |
| 25 mM | 0.1285 mL | 0.6425 mL | 1.2849 mL | 3.2123 mL | |
| 30 mM | 0.1071 mL | 0.5354 mL | 1.0708 mL | 2.6769 mL | |
| 40 mM | 0.0803 mL | 0.4015 mL | 0.8031 mL | 2.0077 mL | |
| 50 mM | 0.0642 mL | 0.3212 mL | 0.6425 mL | 1.6062 mL | |
| 60 mM | 0.0535 mL | 0.2677 mL | 0.5354 mL | 1.3385 mL | |
| 80 mM | 0.0402 mL | 0.2008 mL | 0.4015 mL | 1.0039 mL | |
| 100 mM | 0.0321 mL | 0.1606 mL | 0.3212 mL | 0.8031 mL |
Pomalidomide-propargyl Related Classifications
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