Prenylterphenyllin
Prenylterphenyllin (Compound 1) is an antibacterial agent. Prenylterphenyllin can be isolated from marine-derived fungus Aspergillus candidus IF10. Prenylterphenyllin has cytotoxic activity against KB3-1 cells with an IC50 of 8.5 mg/mL. Prenylterphenyllin also has antibacterial activities against Xanthomonas oryzae and Erwinia amylovora with MICs of both 20 μg/mL.
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- CAS No.: 959124-85-7
- Formule: C25H26O5
- Masse moléculaire:406.47
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
3.62 μM
Compound: 8
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Cytotoxicity against human A549 cells by SRB assay
Cytotoxicity against human A549 cells by SRB assay
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[PMID: 21486068] |
| HepG2 | IC50 |
2.74 μM
Compound: 5
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Cytotoxicity against human HepG2 cells by SRB assay
Cytotoxicity against human HepG2 cells by SRB assay
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[PMID: 29407953] |
| HL-60 | IC50 |
2.75 μM
Compound: 8
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Cytotoxicity against human HL60 cells by MTT assay
Cytotoxicity against human HL60 cells by MTT assay
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[PMID: 21486068] |
| P388 | IC50 |
1.99 μM
Compound: 8
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Cytotoxicity against mouse P388 cells by MTT assay
Cytotoxicity against mouse P388 cells by MTT assay
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[PMID: 21486068] |
Chemical Information
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CAS No. 959124-85-7
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Masse moléculaire 406.47
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Formule C25H26O5
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SMILES
OC1=CC=C(C2=CC(OC)=C(C3=CC=C(C(C/C=C(C)\C)=C3)O)C(O)=C2OC)C=C1
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Structure Classification
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Initial Source
Aspergillus candidus
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Wei H, Inada H, et al. Prenylterphenyllin and its dehydroxyl analogs, new cytotoxic substances from a marine-derived Fungus Aspergillus candidus IF10. J Antibiot (Tokyo). 2007 Sep;60(9):586-90. [Content Brief]
[2]. El-Hawary SS, et al. Natural product diversity from the endophytic fungi of the genus Aspergillus. RSC Adv. 2020 Jun 9;10(37):22058-22079. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Prenylterphenyllin Related Classifications
HY-N16065 Related Classifications
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