959124-85-7
959124-85-7
Chemical Structure
Prenylterphenyllin
- CAS No.: 959124-85-7
- Formula:C25H26O5
- Molecular Weight:406.47
SMILES: OC1=CC=C(C2=CC(OC)=C(C3=CC=C(C(C/C=C(C)\C)=C3)O)C(O)=C2OC)C=C1
Biological Activity: Prenylterphenyllin (Compound 1) is an antibacterial agent. Prenylterphenyllin can be isolated from marine-derived fungus Aspergillus candidus IF10. Prenylterphenyllin has cytotoxic activity against KB3-1 cells with an IC50 of 8.5 mg/mL. Prenylterphenyllin also has antibacterial activities against Xanthomonas oryzae and Erwinia amylovora with MICs of both 20 μg/mL[1][2].
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Prenylterphenyllin | Prenylterphenyllin (Compound 1) is an antibacterial agent. Prenylterphenyllin can be isolated from marine-derived fungus Aspergillus candidus IF10. Prenylterphenyllin has cytotoxic activity against KB3-1 cells with an IC50 of 8.5 mg/mL. Prenylterphenyllin also has antibacterial activities against Xanthomonas oryzae and Erwinia amylovora with MICs of both 20 μg/mL. | |||||||||||||||||||||
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References
- [1]. Wei H, Inada H, et al. Prenylterphenyllin and its dehydroxyl analogs, new cytotoxic substances from a marine-derived Fungus Aspergillus candidus IF10. J Antibiot (Tokyo). 2007 Sep;60(9):586-90. [Content Brief]
- [2]. El-Hawary SS, et al. Natural product diversity from the endophytic fungi of the genus Aspergillus. RSC Adv. 2020 Jun 9;10(37):22058-22079. [Content Brief]
Keywords
