Ramelteon (Standard)
Ramelteon (Standard) is the analytical standard of Ramelteon. This product is intended for research and analytical applications. Ramelteon is a potent, highly selective, and orally active agonist of MT1/MT2 with Ki values of 14 and 112 pM, respectively. Ramelteon has the potential for the research of insomnia. Ramelteon consistently reduces sleep onset after long-term treatment, with no next-morning residual effects or rebound insomnia or withdrawal symptoms upon discontinuation.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 98%
- CAS No.: 196597-26-9
- Formule: C16H21NO2
- Masse moléculaire:259.34
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Pureté et documentation
-
Help & FAQs
-
HY-A0014
RamelteonMT1/2 Inhibitor -
HY-B0075
MelatoninMelatonin Receptor Activator -
HY-14803
TasimelteonDual Melatonin Receptor Agonist -
HY-101254
LuzindoleMelatonin Receptor Antagonist -
HY-17038
AgomelatineMT1/2 Agonist -
HY-100609
4-P-PDOTMT2 Receptor Antagonist -
HY-B0075R
Melatonin (standard)Melatonin Receptor Activator -
HY-B0075S
Melatonin-d4Stable Isotope -
HY-101358
8-M-PDOTMT2 Receptor Agonist -
HY-138626
ACH-000143Melatonin Receptor Agonist -
HY-B0282
Acetylcholine chlorideCholinergic Agonist -
HY-17038R
Agomelatine (Standard)MT1/2 Agonist
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 196597-26-9
-
Masse moléculaire 259.34
-
Formule C16H21NO2
-
SMILES
O=C(NCC[C@H]1C2=C(C=CC3=C2CCO3)CC1)CC
-
Synonyms
TAK-375 (Standard)
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Kato K, et al. Neurochemical properties of ramelteon (TAK-375), a selective MT1/MT2 receptor agonist. Neuropharmacology. 2005;48(2):301-310. [Content Brief]
[2]. Mayer G, et al. Efficacy and safety of 6-month nightly ramelteon administration in adults with chronic primary insomnia. Sleep. 2009;32(3):351-360. [Content Brief]
[3]. Hirai K, et al. Ramelteon (TAK-375) accelerates reentrainment of circadian rhythm after a phase advance of the light-dark cycle in rats. J Biol Rhythms. 2005;20(1):27-37. [Content Brief]
[4]. Miyamoto M, et al. The sleep-promoting action of ramelteon (TAK-375) in freely moving cats. Sleep. 2004;27(7):1319-1325. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Ramelteon (Standard) Related Classifications
HY-A0014R Related Classifications
Powered by Bioz