RI-OR2-TAT
RI-OR2-TAT is a brain-penetrant inhibitor of β-Amyloid oligomerization, which is produced by adding the HIV protein transduction domain TAT to RI-OR2. RI-OR2-TAT binds to Aβ42 fibrils with a Kd value of 58-125 nM. RI-OR2-TAT reduces Aβ aggregation and plaque levels, reduces activation of microglia and oxidative damage, and increases the number of young neurons in the dentate gyrus.
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- CAS No.: 1430219-69-4
- Formule: C117H201N49O23
- Masse moléculaire:2662.16
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Activité biologique
Chemical Information
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CAS No. 1430219-69-4
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Masse moléculaire 2662.16
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Formule C117H201N49O23
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Sequence
Ac-{d-Arg}-Gly-{d-Phe}-{d-Phe}-{d-Val}-{d-Leu}-{d-Lys}-Gly-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Gln}-{d-Arg}-{d-Arg}-{d-Lys}-{d-Lys}-{d-Arg}-Gly-{d-Tyr}-NH2
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Sequence Shortening
Ac-{d-Arg}-G-{d-Phe}-{d-Phe}-{d-Val}-{d-Leu}-{d-Lys}-G-{d-Arg}-{d-Arg}-{d-Arg}-{d-Arg}-{d-Gln}-{d-Arg}-{d-Arg}-{d-Lys}-{d-Lys}-{d-Arg}-Gly-{d-Tyr}-NH2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RI-OR2-TAT Related Classifications
HY-P10824 Related Classifications
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