Thalidomide-azacyclohexane
Thalidomide-azacyclohexane is an E3 ligase ligand-linker conjugate containing a CRBN-based ligand and linker, which can be used to synthesize PROTAC.
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- CAS No.: 2229718-43-6
- Formule: C18H19N3O4
- Masse moléculaire:341.37
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
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Help & FAQs
Voir tous les produits spécifiques à Isoform E3 Ligase Ligand-Linker Conjugates
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Activité biologique
Description
IC50 & Target
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Cereblon |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2229718-43-6
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Masse moléculaire 341.37
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Formule C18H19N3O4
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SMILES
O=C1NC(=O)C(N2C(=O)C3=CC=C(C=C3C2=O)C4CCNCC4)CC1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Thalidomide-azacyclohexane Related Classifications
HY-W998261 Related Classifications
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