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Cat. No.: HY-N12603

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Typhatifolin B

Typhatifolin B (Compd 2), an anti-cancer agent, could remarkably induce cell apoptosis and G0/G1 cycle arrest, as well as block cell migration and invasion.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

Formule: C₃₄H₃₂O₅
Masse moléculaire:520.61

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

Typhatifolin B Chemical Structure

Stock

Quantité

Amount: USD 0.00

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Typhatifolin B (Compd 2), an anti-cancer agent, could remarkably induce cell apoptosis and G0/G1 cycle arrest, as well as block cell migration and invasion^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
4T1	IC₅₀	2.82 μM Compound: 2; TTB	Cytotoxicity against mouse 4T1 cells assessed as cell viability by MTT assay Cytotoxicity against mouse 4T1 cells assessed as cell viability by MTT assay	[PMID: 38387332]
A549	IC₅₀	3.21 μM Compound: 2; TTB	Cytotoxicity against human A549 cells assessed as cell viability by MTT assay Cytotoxicity against human A549 cells assessed as cell viability by MTT assay	[PMID: 38387332]
BEAS-2B	IC₅₀	5.27 μM Compound: 2; TTB	Cytotoxicity against human BEAS-2B cells assessed as cell viability by MTT assay Cytotoxicity against human BEAS-2B cells assessed as cell viability by MTT assay	[PMID: 38387332]
HeLa	IC₅₀	2.2 μM Compound: 2; TTB	Cytotoxicity against human HeLa cells assessed as cell viability by MTT assay Cytotoxicity against human HeLa cells assessed as cell viability by MTT assay	[PMID: 38387332]
HFF	IC₅₀	5.91 μM Compound: 2; TTB	Cytotoxicity against human HFF cells assessed as cell viability by MTT assay Cytotoxicity against human HFF cells assessed as cell viability by MTT assay	[PMID: 38387332]
MCF7	IC₅₀	8.64 μM Compound: 2; TTB	Cytotoxicity against human MCF7 cells assessed as cell viability by MTT assay Cytotoxicity against human MCF7 cells assessed as cell viability by MTT assay	[PMID: 38387332]
MDA-MB-231	IC₅₀	4.33 μM Compound: 2; TTB	Cytotoxicity against human MDA-MB-231 cells assessed as cell viability by MTT assay Cytotoxicity against human MDA-MB-231 cells assessed as cell viability by MTT assay	[PMID: 38387332]

In Vitro

Typhatifolin B (Compd 2) exhibits IC₅₀ values of 4.33 μM, 8.64 μM, 2.82 μM, 2.20 μM, 3.21 μM, 5.27 μM in MDA-MB231, MCF-7, 4T1, Hela, A549, BEAS-2B, HFF cells, respectively^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Masse moléculaire 520.61
Formule C₃₄H₃₂O₅
SMILES

O=C1C[C@@](OC2=C1C(O)=C([C@@](/C=C/C[C@@H](O)CCC3=CC=CC=C3)([H])C4=CC=CC=C4)C(O)=C2)([H])C5=CC=CC=C5
Structure Classification
- Flavonoids
- Flavonones
Initial Source
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Yu-Peng Li, et al. Rare flavanone-diarylheptanoid hybrids from Typha angustifolia shows anti breast cancer activity via activating TGF-β1/Smad signaling pathway. European Journal of Medicinal Chemistry. Volume 268, 15 March 2024, 116220.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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