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Vadastuximab

(Synonyms: Anti-Human CD33 Recombinant Antibody)
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Vadastuximab (Anti-Human CD33 Recombinant Antibody) is a humanized monoclonal antibody targeting CD33. Vadastuximab can be used to synthesize an ADC compound, Vadastuximab talirine.

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  • Pureté: 99.23%
  • CAS No.: 1436390-63-4
  • Masse moléculaire:144.78 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Vadastuximab
  • Experimental Validation Results for Vadastuximab
  • Experimental Validation Results for Vadastuximab
  • Experimental Validation Results for Vadastuximab
  • Vadastuximab Chemical Structure
    Vadastuximab Chemical Structure
CAS No.: 1436390-63-4
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Vadastuximab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Flow Cytometry analysis of THP-1 cells labelling Vadastuximab (red) with Vadastuximab Antibody (anti-Vadastuximab) (HY-P99037). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃.Human IgG1 kappa isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • 1/16

    Loaded Siglec-3/CD33 Protein, Human (HEK293, Fc-His, HY-P72472) on NTA biosensor, can bind Vadastuximab with an affinity constant of 8.459E-11 M as determined in BLI assay.

  • 1/16

    Immobilized Siglec-3/CD33 Protein, Human (HEK293, hFc, HY-P73642) can bind Vadastuximab. The EC50 for this effect is 5.963 ng/mL.

  • Vadastuximab Chemical Structure
    1/16
  • Vadastuximab
  • Flow Cytometry analysis of THP-1 cells labelling Vadastuximab (red) with Vadastuximab Antibody (anti-Vadastuximab) (HY-P99037). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then cells were stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃.Human IgG1 kappa isotype Control (HY-P99001, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).
  • Loaded Siglec-3/CD33 Protein, Human (HEK293, Fc-His, HY-P72472) on NTA biosensor, can bind Vadastuximab with an affinity constant of 8.459E-11 M as determined in BLI assay.
  • Immobilized Siglec-3/CD33 Protein, Human (HEK293, hFc, HY-P73642) can bind Vadastuximab. The EC50 for this effect is 5.963 ng/mL.