(Z)-Broparestrol
(Z)-Broparestrol is a prostaglandin synthetase inhibitor with an IC50 of 7.0 μM in cattle. (Z)-Broparestrol inhibits prostaglandin synthetase activity in bovine seminal vesicle microsomes. (Z)-Broparestrol is applicable for acne-related research.
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- CAS No.: 22393-63-1
- Formule: C22H19Br
- Masse moléculaire:363.29
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
(Z)-Broparestrol (BROPARESTROL Z) inhibits prostaglandin synthetase activity in bovine seminal vesicle microsomes with an IC50 of 7.0 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 22393-63-1
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Masse moléculaire 363.29
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Formule C22H19Br
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SMILES
Br/C(C1=CC=CC=C1)=C(C2=CC=CC=C2)\C3=CC=C(C=C3)CC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Gilbert J, et al. Inhibition of prostaglandin synthetase by di- and triphenylethylene derivatives: a structure-activity study. Journal of medicinal chemistry. 1983 May;26(5):693-9. [Content Brief]
[2]. Toscani S, et al. Overt and hidden polymorphism in the binary system involving the Z- and E- isomers of broparestrol. Int J Pharm. 2025 Jan 25;669:125060. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(Z)-Broparestrol Related Classifications
HY-187157 Related Classifications
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