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Cat. No.: HY-W665208

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Zapotin

Zapotin is a member of the polymethoxyflavones, which are natural polyphenols from the group of flavonoid. Zapotin exhibits antidepressant, anticancer, antifungal, and antioxidant activity. Zapotin is a chemopreventive and chemotherapeutic agent. Zapotin can result in a reduction of large aberrant crypt foci in CF-1 mouse model. Zapotin inhibits autophagosome formation. Zapotin has inhibitory activity in mouse mammary organ culture with an IC₅₀ of 50 µg/mL.

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CAS No.: 14813-19-5
Formule: C₁₉H₁₈O₆
Masse moléculaire:342.34

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Zapotin Chemical Structure

CAS No.: 14813-19-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Cellular Effect

Cell Line	Type	Value	Description	References
HepG2	IC₅₀	7.6 μM Compound: 1, zapotin	Inhibition of TPA-induced NF-kappaB activity in HepG2 cells Inhibition of TPA-induced NF-kappaB activity in HepG2 cells	[PMID: 17228877]
HL-60	ED₅₀	0.5 μM Compound: 1, zapotin	Induction of differentiation in human HL60 cell line Induction of differentiation in human HL60 cell line	[PMID: 17228877]
T-24	IC₅₀	3.4 μM Compound: 1, zapotin	Inhibition of TPA-induced ODC activity in T24 cells Inhibition of TPA-induced ODC activity in T24 cells	[PMID: 17228877]

Chemical Information

CAS No. 14813-19-5
Masse moléculaire 342.34
Formule C₁₉H₁₈O₆
SMILES

COC1=CC=C2OC(C3=C(C=CC=C3OC)OC)=CC(C2=C1OC)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Strawa, J. W., et al., (2021). Zapotin, a Polymethoxyflavone, with Potential Therapeutic Attributes. International journal of molecular sciences, 22(24), 13227. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

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Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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