Calcium trinatrium diethylenetriaminepentaacetic acid hydrate
Based on 1 Customer Validation
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) is a metal chelator and a useful antidote (such as acute cadmium intoxication). Diethylenetriaminepentaacetic acid calcium trisodium salt hydrate is a nontoxic inhibitor of CMV replication.
For research use only. We do not sell to patients.
- Purity : 99.87%
- CAS No.: 207226-35-5
- Formula: C14H20CaN3Na3O11
- Molecular Weight:515.37
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
The antiviral activity of Calcium trinatrium diethylenetriaminepentaacetic acid hydrate is suppressed by metal ions with a decreasing potency order of Mn2+/Zn2+>Fe2+>Cu2+>Fe3+. Diethylenetriaminepentaacetic acid calcium trisodium salt hydrate inhibits CMV L-antigen production with EC50 ranging from 6.1 to 9.9 μM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 207226-35-5
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Appearance Solid
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Molecular Weight 515.37
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Formula C14H20CaN3Na3O11
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Color White to off-white
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SMILES
O=C(O[Na])CN(CC([O-])=O)CCN(CC(O[Na])=O)CCN(CC(O[Na])=O)CC([O-])=O.[Ca+2].O.[x]
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Synonyms
Ca-DTPA trisodium salt hydrate
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
H2O : 175 mg/mL (339.56 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Eybl V, et al. Effect of cadmium chelating agents on organ cadmium and trace element levels in mice. Analyst. 1998;123(1):25-26. [Content Brief]
[2]. Cinatl J Jr, et al. In vitro inhibition of human cytomegalovirus replication by calcium trinatrium diethylenetriaminepentaacetic acid. Antiviral Res. 1996;31(1-2):23-34. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.9404 mL | 9.7018 mL | 19.4035 mL | 48.5088 mL |
| 5 mM | 0.3881 mL | 1.9404 mL | 3.8807 mL | 9.7018 mL | |
| 10 mM | 0.1940 mL | 0.9702 mL | 1.9404 mL | 4.8509 mL | |
| 15 mM | 0.1294 mL | 0.6468 mL | 1.2936 mL | 3.2339 mL | |
| 20 mM | 0.0970 mL | 0.4851 mL | 0.9702 mL | 2.4254 mL | |
| 25 mM | 0.0776 mL | 0.3881 mL | 0.7761 mL | 1.9404 mL | |
| 30 mM | 0.0647 mL | 0.3234 mL | 0.6468 mL | 1.6170 mL | |
| 40 mM | 0.0485 mL | 0.2425 mL | 0.4851 mL | 1.2127 mL | |
| 50 mM | 0.0388 mL | 0.1940 mL | 0.3881 mL | 0.9702 mL | |
| 60 mM | 0.0323 mL | 0.1617 mL | 0.3234 mL | 0.8085 mL | |
| 80 mM | 0.0243 mL | 0.1213 mL | 0.2425 mL | 0.6064 mL | |
| 100 mM | 0.0194 mL | 0.0970 mL | 0.1940 mL | 0.4851 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Calcium trinatrium diethylenetriaminepentaacetic acid hydrate Related Classifications
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