Calcium trinatrium diethylenetriaminepentaacetic acid hydrate  (Synonyms: Ca-DTPA trisodium salt hydrate)

Calcium trinatrium diethylenetriaminepentaacetic acid hydrate (Ca-DTPA trisodium salt hydrate) is a metal chelator and a useful antidote (such as acute cadmium intoxication). Diethylenetriaminepentaacetic acid calcium trisodium salt hydrate is a nontoxic inhibitor of CMV replication^[1][2].

The antiviral activity of Calcium trinatrium diethylenetriaminepentaacetic acid hydrate is suppressed by metal ions with a decreasing potency order of Mn2+/Zn2+>Fe2+>Cu2+>Fe3+. Diethylenetriaminepentaacetic acid calcium trisodium salt hydrate inhibits CMV L-antigen production with EC₅₀ ranging from 6.1 to 9.9 μM^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

515.37

C₁₄H₂₀CaN₃Na₃O₁₁

207226-35-5

O=C(O[Na])CN(CC([O-])=O)CCN(CC(O[Na])=O)CCN(CC(O[Na])=O)CC([O-])=O.[Ca+2].O.[x]

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Eybl V, et al. Effect of cadmium chelating agents on organ cadmium and trace element levels in mice. Analyst. 1998;123(1):25-26.  [Content Brief]

  [2]. Cinatl J Jr, et al. In vitro inhibition of human cytomegalovirus replication by calcium trinatrium diethylenetriaminepentaacetic acid. Antiviral Res. 1996;31(1-2):23-34.  [Content Brief]