1000706-00-2
1000706-00-2
Chemical Structure
KX1-141
- CAS No.: 1000706-00-2
- Formula:C24H20F2N2O2
- Molecular Weight:406.43
IUPAC Name: 7-(3-ethoxyphenyl)-5-fluoro-N-(3-fluorobenzyl)-1H-indole-2-carboxamide
InChIKey: GLBIHDRABBDRFA-UHFFFAOYSA-N
SMILES: O=C(NCC=1C=CC=C(F)C1)C2=CC=3C=C(F)C=C(C=4C=CC=C(OCC)C4)C3N2
Biological Activity: KX1-141 is a non-ATP-competitive Src inhibitor. KX1-141 is largely ineffective in preventing noise-induced hearing loss[1][2].
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KX1-141 | KX1-141 is a non-ATP-competitive Src inhibitor. KX1-141 is largely ineffective in preventing noise-induced hearing loss. | |||||||||||||||||||||
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References
- [1]. Bielefeld EC, et al. Protection from impulse noise-induced hearing loss with novel Src-protein tyrosine kinase inhibitors. Neuroscience research. 2011 Dec;71(4):348-54.
- [2]. Bielefeld EC. Protection from noise-induced hearing loss with Src inhibitors. Drug discovery today. 2015 Jun 1;20(6):760-5.
