1001417-92-0
Chemical Structure
Glucokinase activator 3
- CAS No.: 1001417-92-0
- Formula:C26H33N2O9PS2
- Molecular Weight:612.65
IUPAC Name: diethyl (S)-((2-(3-((1-methoxypropan-2-yl)oxy)-5-(4-(methylsulfonyl)phenoxy)benzamido)thiazol-4-yl)methyl)phosphonate
InChIKey: OQUMCVQSAWPKMT-SFHVURJKSA-N
SMILES: O=C(NC1=NC(CP(OCC)(OCC)=O)=CS1)C2=CC(OC3=CC=C(S(=O)(C)=O)C=C3)=CC(O[C@@H](C)COC)=C2
Biological Activity: Glucokinase activator 3 is an orally active Glucokinase (GK) activator with an AC50 of 38 nM. Glucokinase activator 3 inhibits hERG channel and sodium channel in patch clamp assays. Glucokinase activator 3 exhibits high efficacy in reducing blood glucose in diet-induced obese (DIO) mice. Glucokinase activator 3 has the potential for the research of type 2 diabetes[1].
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Glucokinase activator 3 | 98.36% | Glucokinase activator 3 is an orally active Glucokinase (GK) activator with an AC50 of 38 nM. Glucokinase activator 3 inhibits hERG channel and sodium channel in patch clamp assays. Glucokinase activator 3 exhibits high efficacy in reducing blood glucose in diet-induced obese (DIO) mice. Glucokinase activator 3 has the potential for the research of type 2 diabetes. | ||||||||||||||||||||
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Keywords
