1001644-68-3
Chemical Structure
Antimicrobial peptide BP100
- CAS No.: 1001644-68-3
- Formula:C72H125N17O12
- Molecular Weight:1420.87
InChIKey: QIQRVOMSZCHJLT-AQKDKPMWSA-N
SMILES: OC(C=C1)=CC=C1C[C@@H](C(N[C@H](C(N)=O)CC(C)C)=O)NC([C@H](CCCCN)NC([C@H](CC(C)C)NC([C@H]([C@@H](C)CC)NC([C@H](CCCCN)NC([C@H](CCCCN)NC([C@@H](NC([C@H](CC(C)C)NC([C@H](CCCCN)NC([C@@H](N)CCCCN)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)=O
Biological Activity: Antimicrobial peptide BP100 is a cecropin-α-melittin hybrid linear undecapeptide that exerts bactericidal activity against bacteria through non-specific, amphipathicity-driven membrane damage. Antimicrobial peptide BP100 exhibits in vitro antimicrobial activity against a variety of plant and human pathogens. Antimicrobial peptide BP100 can be used in studies related to bacterial infections, such as those involving phytopathogenic Gram-negative bacteria[1][2].
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Antimicrobial peptide BP100 | Antimicrobial peptide BP100 is a cecropin-α-melittin hybrid linear undecapeptide that exerts bactericidal activity against bacteria through non-specific, amphipathicity-driven membrane damage. Antimicrobial peptide BP100 exhibits in vitro antimicrobial activity against a variety of plant and human pathogens. Antimicrobial peptide BP100 can be used in studies related to bacterial infections, such as those involving phytopathogenic Gram-negative bacteria. | |||||||||||||||||||||
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References
- [1]. Oddo A, et al. An Amphipathic Undecapeptide with All d-Amino Acids Shows Promising Activity against Colistin-Resistant Strains of Acinetobacter baumannii and a Dual Mode of Action. Antimicrobial agents and chemotherapy. 2016 Jan;60(1):592-9.
- [2]. Oliveras À, et al. Peptide Conjugates Derived from flg15, Pep13, and PIP1 That Are Active against Plant-Pathogenic Bacteria and Trigger Plant Defense Responses. Applied and environmental microbiology. 2022 Jun 28;88(12):e0057422.
