1006002-58-9
1006002-58-9
Chemical Structure
ICOS-IN-1
- CAS No.: 1006002-58-9
- Formula:C17H14Cl2N2O2
- Molecular Weight:349.21
InChIKey: GNTDIXSFVUOIDD-UHFFFAOYSA-N
SMILES: OC1=C(C2=NNC=C2)C=CC(OCC3=CC=C(Cl)C(Cl)=C3)=C1C
Biological Activity: ICOS-IN-1 (compound 9) is an inhibitor of the interaction between ICOS and ICOS-L (IC50=29.38 μM) and has activity in recognizing immune checkpoints[1].
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ICOS-IN-1 | ICOS-IN-1 (compound 9) is an inhibitor of the interaction between ICOS and ICOS-L (IC50=29.38 μM) and has activity in recognizing immune checkpoints. | |||||||||||||||||||||
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References
Keywords
