1007786-48-2

JNK-IN-23 Chemical Structure
1007786-48-2

Chemical Structure

JNK-IN-23

  • CAS No.: 1007786-48-2
  • Formula:C19H18N4OS2
  • Molecular Weight:382.50

InChIKey: ZYCFQLYFRCQEMK-UHFFFAOYSA-N

SMILES: CC(C1=NC(SC(C)=C2C)=C2C(N1)=O)SC3=NC4=C(N=C3C)C=CC=C4

Biological Activity: JNK-IN-23 (Compound K12) is an inhibitor of JNK. JNK-IN-23 inhibits the proliferation of MDA-MB-231 (GIC50: 30 nM). JNK-IN-23 blocks TNBC metastatic growth in vivo. JNK-IN-23 inhibits the growth of lung metastases by dual targeting of glutaminase-1 (GLS) and pyruvate dehydrogenase complex (PDHC)[1].

Cat. No. Product Name Purity Description Pricing
HY-174211 		JNK-IN-23 JNK-IN-23 (Compound K12) is an inhibitor of JNK. JNK-IN-23 inhibits the proliferation of MDA-MB-231 (GIC50: 30 nM). JNK-IN-23 blocks TNBC metastatic growth in vivo. JNK-IN-23 inhibits the growth of lung metastases by dual targeting of glutaminase-1 (GLS) and pyruvate dehydrogenase complex (PDHC).
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