100929-77-9
Chemical Structure
2',3'-Cyclic NADP disodium
Synonym(s): 2',3'-cNADP+; β-Nicotinamide adenine dinucleotide-2',3'-cyclic phosphate
- CAS No.: 100929-77-9
- Formula:C21H24N7Na2O16P3
- Molecular Weight:769.35
InChIKey: REJNCHGXPBLANE-WUEGHLCSSA-L
SMILES: O=[P](O[P](OC[C@H]([C@H]1O)O[C@]([N+]2=CC=CC(C(N)=O)=C2)([H])[C@@H]1O)([O-])=O)(O[Na])OC[C@H]3O[C@](N4C5=NC=NC(N)=C5N=C4)([H])[C@@](O6)([H])[C@]3([H])O[P]6(O[Na])=O
Biological Activity: 2',3'-Cyclic NADP disodium (2',3'-cNADP+; β-Nicotinamide adenine dinucleotide-2',3'-cyclic phosphate) is a substrate for 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP), an enzyme abundant in myelin. It has been used in a coupled enzyme assay to quantify CNP activity. 2',3'-Cyclic NADP disodium (5 μM) increases calcium overload-induced calcium release and prevents calcium-induced swelling in rat brain mitochondria.
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2',3'-Cyclic NADP disodium | 2',3'-Cyclic NADP disodium (2',3'-cNADP+; β-Nicotinamide adenine dinucleotide-2',3'-cyclic phosphate) is a substrate for 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP), an enzyme abundant in myelin. It has been used in a coupled enzyme assay to quantify CNP activity. 2',3'-Cyclic NADP disodium (5 μM) increases calcium overload-induced calcium release and prevents calcium-induced swelling in rat brain mitochondria. | |||||||||||||||||||||
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