100981-43-9
100981-43-9
Chemical Structure
Ebrotidine
Synonym(s): FI3542
- CAS No.: 100981-43-9
- Formula:C14H17BrN6O2S3
- Molecular Weight:477.42
IUPAC Name: (E)-N'-((4-bromophenyl)sulfonyl)-N-(2-(((2-guanidinothiazol-4-yl)methyl)thio)ethyl)formimidamide
InChIKey: ZQHFZHPUZXNPMF-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C(Br)C=C1)(/N=C/NCCSCC2=CSC(NC(N)=N)=N2)=O
Biological Activity:
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Ebrotidine | 98.08% | Ebrotidine(FI 3542) is a competitive H2-receptor antagonist (Ki= 127. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Ebrotidine (Standard) | ≥98% | Ebrotidine (Standard) is the analytical standard of Ebrotidine. This product is intended for research and analytical applications. 0 | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- Agut J, Sánchez JC, Sacristán A, Action of ebrotidine, ranitidine and cimetidine on the specific binding to histamine H1- and H2-receptors. Arzneimittelforschung. 1997 Apr;47(4A):447-9. [Content Brief]
- Palop D, Agut J, Márquez M, Histamine H2-receptor antagonist action of ebrotidine. Effects on gastric acid secretion, gastrin levels and NSAID-induced gastrotoxicity in the rat. Arzneimittelforschung. 1997 Apr;47(4A):439-46. [Content Brief]
- Konturek SJ, Kwiecien N, Sito E, Effects of ebrotidine on aspirin-induced gastric mucosal damage and blood flow in humans. Scand J Gastroenterol. 1993 Dec;28(12):1047-50. [Content Brief]
- Piotrowski J, Yamaki K, Morita M, Ebrotidine--a new H2-receptor antagonist with mucosal strengthening activity. Biochem Int. 1992 Mar;26(4):659-67. [Content Brief]
Keywords
