101526-83-4
101526-83-4
Chemical Structure
Sematilide
Synonym(s): CK-1752
- CAS No.: 101526-83-4
- Formula:C14H23N3O3S
- Molecular Weight:313.42
IUPAC Name: N-(2-(diethylamino)ethyl)-4-(methylsulfonamido)benzamide
InChIKey: KHYPYQZQJSBPIX-UHFFFAOYSA-N
SMILES: O=C(NCCN(CC)CC)C1=CC=C(NS(=O)(C)=O)C=C1
Biological Activity: Sematilide (CK-1752) is a selective IKr channel blocker. Sematilide causes a concentration-dependent inhibition of the delayed rectifier K+ current (IC50=25 μM). Sematilide is a class III antiarrhythmic agent[1].
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Sematilide | Sematilide (CK-1752) is a selective IKr channel blocker. Sematilide causes a concentration-dependent inhibition of the delayed rectifier K+ current (IC50=25 μM). Sematilide is a class III antiarrhythmic agent. | |||||||||||||||||||||
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