1016897-10-1
Chemical Structure
RV01
- CAS No.: 1016897-10-1
- Formula:C17H13NO2
- Molecular Weight:263.29
IUPAC Name: (E)-5-(2-(quinolin-4-yl)vinyl)benzene-1,3-diol
InChIKey: YRSOXYVELWTHAE-AATRIKPKSA-N
SMILES: OC1=CC(/C=C/C2=CC=NC3=CC=CC=C23)=CC(O)=C1
Biological Activity: RV01 is an analogue of resveratrol, inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol, and exhibits hydroxyl radical scavenging activity[1]. RV01 decreases iNOS expression, with anti-neuroinflammatory activity[2].
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RV01 | 98.06% | RV01 is an analogue of resveratrol, inhibits DNA damage, reduces acetaldehyde dehydrogenase 2 (ALDH2) mRNA expression induced by ethanol, and exhibits hydroxyl radical scavenging activity. RV01 decreases iNOS expression, with anti-neuroinflammatory activity. | ||||||||||||||||||||
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- [1]. Yan Y, et al. Protection of resveratrol and its analogues against ethanol-induced oxidative DNA damage in human peripheral lymphocytes. Mutat Res. 2011 Apr 3;721(2):171-7. [Content Brief]
- [2]. Hou Y, et al. A Novel Quinolyl-Substituted Analogue of Resveratrol Inhibits LPS-Induced Inflammatory Responses in Microglial Cells by Blocking the NF-κB/MAPK Signaling Pathways. Mol Nutr Food Res. 2019 Aug 4:e1801380. [Content Brief]
Keywords