1020719-71-4
1020719-71-4
Chemical Structure
Oxcarbazepine-d4
Synonym(s): GP 47680-d4
- CAS No.: 1020719-71-4
- Formula:C15H8D4N2O2
- Molecular Weight:256.29
IUPAC Name: 10-oxo-10,11-dihydro-5H-dibenzo[b,f]azepine-1,2,3,4-d4-5-carboxamide
InChIKey: CTRLABGOLIVAIY-DNZPNURCSA-N
SMILES: C(N)(=O)N1C=2C(C(=O)CC=3C1=C(C(=C(C3[2H])[2H])[2H])[2H])=CC=CC2
Biological Activity: Oxcarbazepine-d4 (GP 47680-D4) is the deuterium labeled Oxcarbazepine. Oxcarbazepine is a sodium channel blocker[1]. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines[2]. Anti-cancer and anticonvulsant effects[2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Oxcarbazepine-d4 | Oxcarbazepine-d4 (GP 47680-D4) is the deuterium labeled Oxcarbazepine. Oxcarbazepine is a sodium channel blocker. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. Anti-cancer and anticonvulsant effects. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Oxcarbazepine (Standard) | 99.88% | Oxcarbazepine (Standard) is the analytical standard of Oxcarbazepine. This product is intended for research and analytical applications. Oxcarbazepine is a sodium channel blocker. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. Anti-cancer and anticonvulsant effects. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Oxcarbazepine-d10 | Oxcarbazepine-d10 (GP 47680-d10) is deuterium labeled Oxcarbazepine. Oxcarbazepine is a sodium channel blocker. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. Anti-cancer and anticonvulsant effects. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Oxcarbazepine-d4-1 | Oxcarbazepine-d4-1 is deuterium labeled Oxcarbazepine. Oxcarbazepine is a sodium channel blocker. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. Anti-cancer and anticonvulsant effects. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Oxcarbazepine-d8 | Oxcarbazepine-d8-1 is a deuterium of Oxcarbazepine. Oxcarbazepine is a sodium channel blocker. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. Oxcarbazepine-d8-1 has anti-cancer and anticonvulsant effects. | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Oxcarbazepine | 99.90% | Oxcarbazepine is a sodium channel blocker. Oxcarbazepine significantly inhibits glioblastoma cell growth and induces apoptosis or G2/M arrest in glioblastoma cell lines. Anti-cancer and anticonvulsant effects. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
- [2]. Ashley M Thomas, et al. Old Friends With New Faces: Are Sodium Channel Blockers the Future of Adjunct Pain Medication Management?J Pain. 2018 Jan;19(1):1-9. [Content Brief]
- [3]. Ching-Yi Lee,et al. The effects of antiepileptic drugs on the growth of glioblastoma cell lines. J Neurooncol. 2016 May;127(3):445-53. [Content Brief]
