102601-58-1
102601-58-1
Chemical Structure
Z-Gly-Gly-Arg-AMC hydrochloride
- CAS No.: 102601-58-1
- Formula:C28H34ClN7O7
- Molecular Weight:616.07
InChIKey: AYMJBLVMUDFWTM-BOXHHOBZSA-N
SMILES: CC(C1=CC=C(NC([C@H](CCCNC(N)=N)NC(CNC(CNC(OCC2=CC=CC=C2)=O)=O)=O)=O)C=C1O3)=CC3=O.Cl
Biological Activity: Z-Gly-Gly-Arg-AMC hydrochloride is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm)[1][2].
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Z-Gly-Gly-Arg-AMC hydrochloride | Z-Gly-Gly-Arg-AMC hydrochloride is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP) (Ex/Em = 390/480 nm). | |||||||||||||||||||||
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References
- [1]. Tarandovskiy ID, et al. Antiplatelet agents can promote two-peaked thrombin generation in platelet rich plasma: mechanism and possible applications. PLoS One. 2013;8(2):e55688. [Content Brief]
- [2]. Machlus KR, et al. Effects of tissue factor, thrombomodulin and elevated clotting factor levels on thrombin generation in the calibrated automated thrombogram. Thromb Haemost. 2009 Nov;102(5):936-44. [Content Brief]
Keywords
