103295-92-7
103295-92-7
Chemical Structure
Ro 18-3981
- CAS. Nr.: 103295-92-7
- Formula:C24H33N3O8S
- Molecular Weight:523.60
IUPAC Name: 2-propoxyethyl 5-(2-(N-isopropylsulfamoyl)acetyl)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3-carboxylate
InChIKey: VEZRCCZBPXTSNZ-UHFFFAOYSA-N
SMILES: O=C(C1=C(C)NC(C)=C(C(CS(=O)(NC(C)C)=O)=O)C1C2=CC=CC([N+]([O-])=O)=C2)OCCOCCC
Biological Activity: Ro 18-3981 is a dihydropyridine that inhibits cardiac Ca2+ channels. Ro 18-3981 shows higher inhibitory activity when the cell membrane is in a depolarized state (Vh=-20 mV: IC50=2.3 nM; Vh=-50 mV: IC50=100 nM)[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Ro 18-3981 | Ro 18-3981 is a dihydropyridine that inhibits cardiac Ca2+ channels. Ro 18-3981 shows higher inhibitory activity when the cell membrane is in a depolarized state (Vh=-20 mV: IC50=2.3 nM; Vh=-50 mV: IC50=100 nM). | |||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
