10371-86-5
10371-86-5
Chemical Structure
SMU-CX1
- CAS No.: 10371-86-5
- Formula:C18H16N2O
- Molecular Weight:276.33
InChIKey: BKRMCDAOAQWNTG-UHFFFAOYSA-N
SMILES: COC1=CC=C2C(C(C(C)=C3C(C=CN=C3)=C4C)=C4N2)=C1
Biological Activity: SMU-CX1 is a specific TLR3 inhibitor (IC50: 0.11 μM) with IC50 ranging from 0.14-0.33 μM against multiple influenza A virus subtypes. SMU-CX1 inhibits the viral PB2 and NP proteins with an IC50 of 0.43 μM for SARS-CoV-2 activity. SMU-CX1 also inhibits inflammatory factors in host cells, including IFN-β, IP-10, and CCL-5[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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SMU-CX1 | 99.9% | SMU-CX1 is a specific TLR3 inhibitor (IC50: 0.11 μM) with IC50 ranging from 0.14-0.33 μM against multiple influenza A virus subtypes. SMU-CX1 inhibits the viral PB2 and NP proteins with an IC50 of 0.43 μM for SARS-CoV-2 activity. SMU-CX1 also inhibits inflammatory factors in host cells, including IFN-β, IP-10, and CCL-5. | ||||||||||||||||||||
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References
Keywords
