1043922-53-7
1043922-53-7
Chemical Structure
Gü1303
- CAS No.: 1043922-53-7
- Formula:C20H22N4O3
- Molecular Weight:366.41
IUPAC Name: benzyl (S)-(1-(2-cyano-1,2-dimethylhydrazinyl)-1-oxo-3-phenylpropan-2-yl)carbamate
InChIKey: FTJHEEIVOBBMMC-SFHVURJKSA-N
SMILES: CN(N(C([C@@H](NC(OCC1=CC=CC=C1)=O)CC2=CC=CC=C2)=O)C)C#N
Biological Activity: Gü1303 is a potent, reversible, slow-binding cathepsin K (CatK) inhibitor with a Ki of 0.91 nM for mature CatK (mCatK). Gü1303 suppresses the autocatalytic activation of the cathepsin K zymogen[1].
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Gü1303 | Gü1303 is a potent, reversible, slow-binding cathepsin K (CatK) inhibitor with a Ki of 0.91 nM for mature CatK (mCatK). Gü1303 suppresses the autocatalytic activation of the cathepsin K zymogen. | |||||||||||||||||||||
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