1. Metabolic Enzyme/Protease
  2. Cathepsin
  3. Gü1303

Gü1303 

Cat. No.: HY-144812
Handling Instructions

Gü1303 is a potent, reversible, slow-binding cathepsin K (CatK) inhibitor with a Ki of 0.91 nM for mature CatK (mCatK). Gü1303 suppresses the autocatalytic activation of the cathepsin K zymogen.

For research use only. We do not sell to patients.

Gü1303 Chemical Structure

Gü1303 Chemical Structure

CAS No. : 1043922-53-7

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Description

Gü1303 is a potent, reversible, slow-binding cathepsin K (CatK) inhibitor with a Ki of 0.91 nM for mature CatK (mCatK). Gü1303 suppresses the autocatalytic activation of the cathepsin K zymogen[1].

IC50 & Target

Ki: 0.91 nM (mCatK)[1]

Molecular Weight

366.41

Formula

C20H22N4O3

CAS No.
SMILES

CN(N(C([[email protected]@H](NC(OCC1=CC=CC=C1)=O)CC2=CC=CC=C2)=O)C)C#N

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Product Name:
Gü1303
Cat. No.:
HY-144812
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