10441-27-7
Chemical Structure
3-Acetyl-7-Hydroxycoumarin
- CAS No.: 10441-27-7
- Formula:C11H8O4
- Molecular Weight:204.18
IUPAC Name: 3-acetyl-7-hydroxy-2H-chromen-2-one
InChIKey: BRQZHMHHZLRXOO-UHFFFAOYSA-N
SMILES: CC(=O)C1=CC2=C(C=C(C=C2)O)OC1=O
Biological Activity: 3-Acetyl-7-Hydroxycoumarin (Compound 2) is a high selective 17-beta-hydroxysteroid dehydrogenase type 1 (17β-HSD1) inhibitor. 3-Acetyl-7-Hydroxycoumarin shows a significant improvement of the inhibitory potency, with 57% inhibition of 17β-HSD1 at 6 μM. 3-Acetyl-7-Hydroxycoumarin is promising for research of hormone-dependent diseases, such as breast cancer and endometriosis[1].
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3-Acetyl-7-Hydroxycoumarin | 95.17% | 3-Acetyl-7-Hydroxycoumarin (Compound 2) is a high selective 17-beta-hydroxysteroid dehydrogenase type 1 (17β-HSD1) inhibitor. 3-Acetyl-7-Hydroxycoumarin shows a significant improvement of the inhibitory potency, with 57% inhibition of 17β-HSD1 at 6 μM. 3-Acetyl-7-Hydroxycoumarin is promising for research of hormone-dependent diseases, such as breast cancer and endometriosis. | ||||||||||||||||||||
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Keywords
