1049743-58-9

PS-1145 dihydrochloride Chemical Structure
1049743-58-9

Chemical Structure

PS-1145 dihydrochloride

  • CAS No.: 1049743-58-9
  • Formula:C17H13Cl3N4O
  • Molecular Weight:395.67

IUPAC Name: N-(6-chloro-9H-pyrido[3,4-b]indol-8-yl)nicotinamide dihydrochloride

InChIKey: QTDCBADLGJZBHP-UHFFFAOYSA-N

SMILES: O=C(C1=CC=CN=C1)NC2=CC(Cl)=CC3=C2NC4=C3C=CN=C4.[H]Cl.[H]Cl

Biological Activity: PS-1145 (dihydrochloride) is a potent IκB kinase-2 inhibitor with an IC50 value of 88 nM. PS-1145 (dihydrochloride) inhibits activity of NF-κB by blocking IκB kinase phosphorylation in tumor-bearing rats[1].

Cat. No. Product Name Purity Description Pricing
HY-107593 		PS-1145 dihydrochloride PS-1145 (dihydrochloride) is a potent IκB kinase-2 inhibitor with an IC50 value of 88 nM. PS-1145 (dihydrochloride) inhibits activity of NF-κB by blocking IκB kinase phosphorylation in tumor-bearing rats.
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