1056634-68-4
1056634-68-4
Chemical Structure
Momelotinib
Synonym(s): CYT387
- CAS No.: 1056634-68-4
- Formula:C23H22N6O2
- Molecular Weight:414.46
IUPAC Name: N-(cyanomethyl)-4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)benzamide
InChIKey: ZVHNDZWQTBEVRY-UHFFFAOYSA-N
SMILES: O=C(C1=CC=C(C2=NC(NC3=CC=C(N4CCOCC4)C=C3)=NC=C2)C=C1)NCC#N
Biological Activity: Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50a of 11 nM and 18 nM,respectively. CYT387 shows much less activity against JAK3.
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Momelotinib | 98.73% | Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50a of 11 nM and 18 nM,respectively. CYT387 shows much less activity against JAK3. | ||||||||||||||||||||
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Momelotinib (Standard) | ≥98% | Momelotinib (Standard) is the analytical standard of Momelotinib. This product is intended for research and analytical applications. Momelotinib (CYT387) is an ATP-competitive inhibitor of JAK1/JAK2 with IC50a of 11 nM and 18 nM,respectively. CYT387 shows much less activity against JAK3. | ||||||||||||||||||||
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Keywords
