105784-61-0
105784-61-0
Chemical Structure
Temafloxacin hydrochloride
Synonym(s): TMFX hydrochloride; TA-167; A-62254
- CAS No.: 105784-61-0
- Formula:C21H19ClF3N3O3
- Molecular Weight:453.84
IUPAC Name: 1-(2,4-difluorophenyl)-6-fluoro-7-(3-methylpiperazin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
InChIKey: DDVJEYDLTXRYAJ-UHFFFAOYSA-N
SMILES: O=C(C1=CN(C2=CC=C(F)C=C2F)C3=C(C=C(F)C(N4CC(C)NCC4)=C3)C1=O)O.Cl
Biological Activity: Temafloxacin (TMFX) hydrochloride is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin hydrochloride is well tolerated in lower respiratory and genitourinary tract infections[1][2].
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Temafloxacin hydrochloride | Temafloxacin (TMFX) hydrochloride is an orally active quinolone broad-spectrum antibacterial agent. Temafloxacin hydrochloride is well tolerated in lower respiratory and genitourinary tract infections. | |||||||||||||||||||||
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References
- [1]. Hardy DJ, et al. Comparative antibacterial activities of temafloxacin hydrochloride (A-62254) and two reference fluoroquinolones. Antimicrob Agents Chemother. 1987 Nov;31(11):1768-74. [Content Brief]
- [2]. Pankey GA. Temafloxacin: an overview. Am J Med. 1991 Dec 30;91(6A):166S-172S. [Content Brief]
